Swiss ADME properties screening of the phytochemical compounds present in Bauhinia acuminata

Abstract

In modern years, conventional medicinal plants analysis have constantly increased multinationally because plants allow them to complement modern pharmacological approaches. As computer mechanics approach, i.e in silico screening and pharmacokinetic screening can augment active compounds among the candidates and indicate mechanism of action of medicinal plants. The plant is well known for its precautionary action in tuberculosis. It has been established to possess some pharmacological activities such as Cytotoxic [1], antibacterial [2, 3], anti-nociceptive [4], thrombolytic activity [5], antioxidant [6], anthelmintic [7], anti-diarrheal [8], Hepatoprotective [9]. The present focus on the use of in silico ADME tool called Swiss ADME for pharmacological and pharmacognostic profiling of Bauhinia acuminata. The results of these studies can be further carried forward by researcher to investigate the in vitro and in vivo studies to reveal the pharmacological basis of traditional medicinal plants.