Comparison of steroid injection and platelet-rich plasma injection in the treatment of De-Quervain Tenosynovitis

Abstract

Aim: The aim of this study was to evaluate the therapeutic effect of corticosteroid and platelet-rich plasma (PRP) injections in the treatment of De Quervain Tenosynovitis. Methods: The study group comprised of 49 patients with 50 hands divided into two groups. In the corticosteroid group (Group A; n=28), 1 ml of methylprednisolone (40 mg/ml) was injected along with 1 ml of 0.5% bupivacaine. In the PRP group (Group B; n=22), PRP was obtained from the patients’ own blood and injected in a single dose. Patients were evaluated using Visual analogue scale (VAS), the shortened disabilities of the arm, shoulder and hand questionnaire (DASH) at baseline, one and three months after the injection. Results: Overall, 44 females and 5 males were included with 28 hands in Group A and 22 hands in Group B. The CS group had better pain relief, hand function tests at 1 month and at 3 months follow-up, the PRP group had better pain relief, hand function tests than CS group. Conclusion: PRP therapy proves to be more effective in relieving pain than corticosteroid injections in treatment of De-Quervain Tenosynovitis.