Haematological markers as a predicting tool for gallstone induced severe acute pancreatitis

Abstract

Severe acute pancreatitis (SAP) has high morbidity and mortality. Gallstones being the most common cause, warrants study into the haematological markers for swift and easy prediction of gallstone induced SAP. Patients of gallstone induced acute pancreatitis were included in this study. Blood investigations of all patients were sent within one hour of arrival. Computed Tomography (CT) was done after 72 hours of onset of pain. Values of all haematological markers, BISAP and MCTSI were then calculated. 70 patients were included in this study. Area under the ROC curve and cut offs based on these curves for predicting SAP were calculated for NLR, PLR, LMR, RDW, Blood sugar, BISAP (≥3) and MCTSI (>6). Their sensitivity and specificity were then calculated. All tested variables except blood sugar could predict SAP. PLR turned out to the best predictive factor among all. We suggest a combination of NLR and PLR for detecting maximum cases.