Serum IL-10 levels in acute coronary syndrome Wistar mice model with Salam leaf extract (Syzygium polyanthum) administration

Abstract

Coronary Heart Disease (CHD) has been one of the main causes of death in the world. Syzygium polyanthum or locally known bay leaf (daun salam) is a plant that has been well known by the community. At present, S. polyanthum leaves are reported to have anti-inflammatory, antioxidant, antidiabetic, antimicrobial, antihypertensive, antitumor, antidiarrheal, acetyl cholinesterase inhibition, and lipase inhibitory activity.This study was to prove the effect of bay leaf extract (Syzygium polyanthum) on serum interleukin (IL)-10 levels in the heart of Wistar Strain Mice Model with Acute Coronary Syndrome (ACS). This is an experimental study to compare the IL-10 level in ACS mice with and without bay leaf extract administration, on day 1, 4, 7, and 14. The result showed that the treatment group has the higher levels of IL-10, which shows the potential advantages of bay leaf extract administration in patients with ACS.