In vitro anti-oxidant activity of aqueous and methanol extracts of Catharanthus roseus (L) G. Don

Abstract

Catharanthus roseus is a well-known medicinal plant, a potential source of antioxidants, the compounds like polyphenols, flavonoids, and phenolic are present in the herbs; act as natural antioxidants which are responsible for inhibiting or preventing the consequence of oxidative stress by scavenging free radicals. In this study, antioxidant potential of aqueous and methanol extracts of C. roseus was determined by DPPH scavenging assay and Fe3+ reducing power assay. Both the extracts showed antioxidant activities at various concentrations. When compared to aqueous extracts methanol extracts shows highest amount of phenolic content, DPPH scavenging capacity and reducing capacity. The antioxidant potential of C. roseus extracts significantly correlated with the phenolic content of extracts. Ascorbic acid taken as control showed highest antioxidant power in the study.