Clinical profile of patients with cholelithiasis at a tertiary care hospital

Abstract

Gallstones represent a failure to maintain certain biliary solutes, primarily cholesterol and calcium salts in a solubilized state. An important biliary precipitate in gallstone pathogenesis is biliary sludge, which refers to a mixture of cholesterol crystals, calcium bilirubinate granules, and a mucin gel matrix. The general bio-data of patient regarding his name, age, sex, religion, occupation, socio-economic status and address was collected. A detailed history was taken with special reference to duration of right upper quadrant pain or epigatric pain, its periodicity, its aggravation by fatty meals and relief by oral or parenteral analgesics. 16 patients presented with nausea along with pain abdomen and 78 patients presented with vomiting, whereas 94 patients presented with both. Jaundice was seen in 33 patients.