Effect of Aloe vera gel and mint tea on letrozole induced PCOS in rat model

Abstract

The present study was conducted to investigate the effect of Aloe vera gel and Mint tea on Polycystic ovary syndrome in rat model. Adult female Wistar rat (150-200gm) rats treated orally with letrozole at the dose of 1mg/kg body wt. daily for 21 days for PCOS development, and were further treated with Aloe vera gel (1ml /rat p.o) and Mint tea (provided ad-lib) for 30 days. Parameters that were evaluated include b.wt, oestrus cyclicity, Ultrasonography, FSH and LH Level and Histopathology of ovary. Combination treatment of Aloe vera gel and Mint tea for 30 days in PCOS rats demonstrated most beneficial effects by restoring ovarian structure, hormonal level along with oestrus cyclicity. This preliminary study explores the effectiveness of Aloe vera gel and Mint tea in prevention and treatment of PCOS conditions.