Efficacy of platelet rich plasma in the management of early osteoarthritis of knee

Abstract

Aim: To assess the efficacy of Platelet rich plasma in patients with early Osteoarthritis knee at AIMS, B.G.NAGARA during AUGUST 2018 to DECEMBER 2020. Materials and Method: The study was conducted in the Department of Orthopaedics, Adichunchanagiri Institute of Medical Sciences, B. G. NAGARA after obtaining ethical clearance. This study consisted of 70 adult patients of either sex visiting outpatient department of the hospital. Patients diagnosed with early osteoarthritis knee were included in the study during the period from December 2018 to JUNE 2020. Observation and Results: The mean age in our study is 56.5 years. The mean IKDC score increased from baseline of 38.99 to 63.86 at 6 months follow up. After 2 months of follow up, there was significant improvement of IKDC score in both the genders. The IKDC score showed improvement in all four age groups. Minor complications were reported. Conclusion: On the basis of the current evidence, PRP injections reduced pain more effectively in Osteoarthritis of the knee. PRP injections can be used to treat early osteoarthritis of knee with significant improvement in function and possibly postpone the need for surgical intervention. More large randomized multicentric studies of good quality and less bias are needed to test whether PRP injections can be used as a routine treatment option in management of patients with Osteoarthritis of knee.