Comparative impacts of linear alkyl benzene sulfonate (LAS) in the liver enzymes of Clarias gariepinus juvenile and adult

Abstract

The impact of a commercial detergent containing Linear alkyl benzene Sulfonate, a household cleaning agent was investigated to determine to what extent it alters liver enzymes of Clarias gariepinus with mean weight of 246.30± 14.12g SD and mean length of 16.15±1.40cm SD for juveniles and mean weight of 850.00±10.22g SD and mean length 29.20± 7.12 cm SD for adult. After series of range finding test, the two life stages were exposed to chronic concentrations of 10.00, 20.00, 30.00, 40.00 and 50.00mg/l of detergent for 30 days in a renewable bio assay. It was observed that detergent respectively raised AST activities in the liver of juvenile fish by 35.52 and 33.20% at 10.00 and 20.00mg/l higher than that of adult fish while the reverse was observed at 40.00mg/l where that of adult fish was 138.47% higher than that of juvenile fish. At 30.00 and 50.00mg/l, AST activities in juvenile fish were respectively 27.85 and 6.98% less than control whereas that of adult fish was 93.18 and 190.90% higher than control. ALT activities in adult fish were respectively 27.52, 49.08, 55.96, 63.30 and 63.30% lower than control at 10.00, 20.00, 30.00, 40.00 and 50.00mg/l and that of adult was higher than that of control by 45.00% at 10.00mg/l; 10.00% at 30.00mg/l, lower than control by 60.00% at 20.00mg/l and same with control at 40.00mg/l. At 10.00, 20.00 and 30.00mg/l, ACP activities were respectively 90.93, 31.97 and 2.95% while at 40.00 and 50.00mg/l, it was 40.44 and 42.30% higher than that of control in adult fish. ACP activities in juvenile fish was same with control at 40.00 and 50.00mg/l. ALP activities in the liver of juvenile fish was 31.90 and 46.68% higher than that of adult fish whereas at 30.00, 40.00 and 50.00mg/l, it was respectively 34.65, 42.07 and 48.26% higher than control in the adult fish and 49.97, 50.00 and 49.64% lower than control in juvenile fish.