Pharmacological and phytochemical profile of Trachyspermum ammi: evidence from the traditional medicine and recent research

Abstract

Medicinal plants always played an important role in the health development of mankind. Trachyspermum ammi is one of the oldest spice plants which, due to its economic importance and significant pharmaceutical industry applications, are considered as one of the world’s most important medicinal plants. In order to gather the information the keywords Trachyspermum ammi, therapeutic, and pharmacology have been searched until August 30, 2020 from journals accessible in databases such as Science Direct, Scopus, EBSCO, Medline, PubMed, Embase, SID, and Iran Medex. The results showed that this plant has various pharmacological properties including analgesic, antioxidant, digestive, anti-cancer activity, anti-inflammatory, antifungal, Anti-bacterial and estrogenic effects which are probably due to the presence of aromatic compounds such as carvone, limonene, thymol, hygroscopic saponin, crystalline flavone and dillapiole. Trachyspermum ammi possesses various pharmacological properties and play an important role in human health; hence, it might be used for different drug productions.