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Evaluation and comparison of protective actions resveratrol and vitamin-e in 5-flourouracil induced hepatotoxicity
The Pharma Innovation · 2021 · Vol. 10(3) · pp. 22–26
Belgode Narasimha Harish✉(Kerala Veterinary and Animal Sciences University)P. Shivakumar(P.V. Narsimha Rao Telangana Veterinary University)Bdp Kala Kumar(P.V. Narsimha Rao Telangana Veterinary University)B Ramya(P.V. Narsimha Rao Telangana Veterinary University)M Usha Rani(P.V. Narsimha Rao Telangana Veterinary University)Anil Kumar Banothu(Kerala Veterinary and Animal Sciences University)Venkata Rao KV(P.V. Narsimha Rao Telangana Veterinary University)
Abstract
We investigate the protective effects of resveratrol and vitamin-E against 5-flourouracil induced hepatotoxicity in rats. Experimental rats were treated with 5-FU (20 mg/kg b.wt.) i.p. on day 1, 3, 7 to induce hepatotoxicity, evident by significant (p
Liver Disease Diagnosis and TreatmentDrug-Induced Hepatotoxicity and ProtectionSirtuins and Resveratrol in MedicineResveratrolVitaminPharmacologyMedicineEndocrinology
Citations
2
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0.30
field-weighted impact
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20
Percentile
58%
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Citations per year
References
Therapeutic potential of resveratrol: the in vivo evidence
Nature Reviews Drug Discovery · 2006 · 3,859 citations
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