Evaluation of chemical constituents of Lyonia ovalifolia (wall.) Drude (1897) leaves extract

Abstract

Lyonia ovalifolia has been used in a folk medicine for the treatment of wounds, cuts, burns, and scabies by different communities in Nepal. The present study is intended to evaluate the phytochemical constituents present in the leaf of plant and to subject methanol and hexane extract of plant leaf to phytochemical screening, GC-MS analysis, HPLC and FTIR analysis. Phytochemical screening of methanol extract revealed the presence of phenolic compounds, flavonoids, glycosides, tannins, xanthoprotein, quinones and saponins. Hexane extracts showed the presence of resins and quinones. The bioactive compounds of L. ovalifolia leaves have been evaluated using GC-MS, HPLC and FTIR. Fourteen chemical constituents have been identified through GC-MS analysis, among that the major constituents are Cyclopental [c] pyran-1(3H)one, hexahydro4,7-dimetyl (27.88%), Cyclopentene, 1-(2-propenyl) (16.52%), Diglycerol (14.99%) and others. The compounds identified through GC-MS analysis were probably helpful for the cure of many infections. The mass spectra of the compounds formed by the methanol extract are matched with NIST library.