Recent progress in surface plasmon resonance based sensors: A comprehensive review

Abstract

In the recent years, researchers have contributed substantially in the field of Surface Plasmon Resonance (SPR) sensors and its applications. SPR sensors show the salient features, such as label-free detection, real-time monitoring, small sample size, furnish accurate outcomes at low cost, and smooth handling. Moreover, the SPR sensors are also well-known because of its quantitative and qualitative excellent performance in real-time applications, including drug discovery, environment monitoring, food safety, medical diagnosis, clinical diagnosis, biological studies, and biomolecule interactions. This paper exhibits a comprehensive review of SPR based sensors, such as prism-based SPR with the applications (e.g., biomolecule interaction, medical diagnostic, etc.), fiber-based SPR, and waveguide-based SPR. Furthermore, we summarized the modern designs and techniques with their limitations and challenges in detail. The erudition outlined in this paper can be given an exceptional benefit for the researchers and industry people in the field of SPR based sensors.