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Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial
Intensive Care Medicine · 2017 · Vol. 43(11) · pp. 1551–1561
Melanie Meersch✉(University Hospital Münster)C. G. Schmidt(University Hospital Münster)A. Hoffmeier(University of Münster)Hugo Van Aken(University Hospital Münster)Carola Wempe(University Hospital Münster)Joachim Gerß(University of Münster)Alexander Zarbock(University Hospital Münster)
Abstract
An implementation of the KDIGO guidelines compared with standard care reduced the frequency and severity of AKI after cardiac surgery in high risk patients. Adequately powered multicenter trials are warranted to examine mortality and long-term renal outcomes.
Acute Kidney Injury ResearchCardiac Arrest and ResuscitationCardiac, Anesthesia and Surgical OutcomesMedicineAcute kidney injuryClinical endpointKidney diseaseCardiac surgeryRandomized controlled trialDialysisIntensive care medicineInternal medicineIntensive care unit
MeSH terms
Hemodynamic MonitoringAgedAngiotensin-Converting Enzyme InhibitorsCardiopulmonary BypassCreatinineFemaleHumansLength of StayMaleMiddle AgedPostoperative ComplicationsRisk FactorsSeverity of Illness IndexBiomarkersPractice Guidelines as Topic
Funding
- Astute Medical
- Deutsche Forschungsgemeinschaft
- European Society of Intensive Care Medicine
Citations
868
FWCI
55.68
field-weighted impact
References
36
Percentile
100%
vs. same field & year
Citations per year
References
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury
Critical Care · 2013 · 1,348 citations
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