Clinical study of outcome in the management of BPH with obstructive nephropathy

Abstract

Background: Benign Prostate Hyperplasia (BPH) is a common disease in adult men and its incidence is age related. While the underlying mechanism for developing renal failure associated with benign prostatic hyperplasia is likely multifactorial and co-morbid factors in elderly men may contribute to renal impairment. We aimed that to determine the association of benign prostatic obstruction with nephropathy. Materials and Methods: A Prospective study was conducted at JSS Hospital, Karnataka, between June 2010 to June 2012. A total 30 patients were included after informed consent. Blood samples were collected from all the subjects. IPSS, QoL Score, Residual urine, Serum Creatinine, Prostatic volume and Hemodialysis was done. Results: The present study evaluates the IPSS and QoL Score, Residual urine, Serum Creatinine, Prostatic volume and Hemodialysis in patients with BPH showed a positive relation with nephropathy. Along with that we analyzed all the parameters pre and post OP IPSS (24.75 ± 1.88, 14.27±3.66), QoL Score (4.65 ±0.66, 1.93±0.75), Residual urine 442.48±225.65, 44.89± 47.50), Serum Creatinine (3.04± 2.13 1.28±0.49), and Hemodialysis (3(10%), 2 (6%). Conclusion: This study concludes Strong inter-relation between the two such that BPH can cause renal failure while renal failure can influence the management of BPH and its outcome.