Secondary metabolites assessment: In vitro Antiarthritic and antihemolytic potential of various extracts of ginger

Abstract

Herbal medicines are are one of the dietary supplements to maintain or improve health. They are used as prophylactic and therapeutic agents. Zingiber offecinale is widely used around the world in food as the spice. The primary pungent agents (phenylalkylketones or vanilyl ketones) of ginger are gingerol with other general analogues such as the shogoals, paradole and zinger one. Present study is of primary and secondary metabolite assessment based in which main focus is on anti-arthritic and antihemolytic activity of ginger extracts. Preliminary screening shows the presence of carbohydrate and protein, alkaloids saponins, steroids and tannins. In vitro anti-arthritic study showed the inhibition of protein denaturation which indicated that the ginger extracts are capable of controlling the production of auto antigens. Another study of antihemolytic activity indicate the capacity of Ginger extract to reduce hemolysis of RBC. Further the FTIR- spectra of Zingiber has also been performed for rapid determination and identification of various functional groups responsible for the medicinal properties such as phenolics, ether, aromatics, carboxylic acid and alcohol.