Diversity oriented green synthesis of novel benzoxazole clubbed chromene arylsulfonamide derivatives using reusable catalyst

Abstract

A group of novel heterocyclic arylsulfonamide derivatives were synthesized by three steps process using the organic and inorganic catalyst in less solvent at ambient temperature. One out of the three-steps process, one-pot multiple component reaction using the reusable organic catalyst. These compounds reactions proceed through Knoevenagel condensation accompanied by Michael addition to obtaining suspicious products. The synthesized compound’s structure was characterized by spectral data (UV-vis, FTIR and 1H-NMR). Subsequently, the obtained novel final products are “benzoxazole clubbed chromene aryl sulfonamide derivatives”. The green synthesis process was used to obtain optimum yield products to fulfil the required conditions such as nontoxic, inexpensive, minimum solvent and reusable catalyst.