A phyto-pharmacological screening for whole plant of Ixora pavetta

Abstract

The world population is facing major problem with liver and kidney disorders. Despite its frequent occurence, high morbidity and high mortality, its medical management is currently inadequate, no exact therapy has been successfully prevented the progression of nephritis and hepatic diseases. The plant Ixora pavetta belongs to family Rubiaceae. Many researchers have screened for analgesic, anti-inflammatory, anti-ulcer, anti-oxidant, anti-microbial activities on leaves and flowers of Ixora pavetta. The selected plant is traditionally used to treat the visceral obstructions, haemorrhoids, dropsy, piles, hepatotoxicity etc. The genus Ixora has been reported to possess different classes of phytochemical constituent’s mainly aromatic acrid oil, tannin, saponin, carbohydrates, flavonoids. Since there is a claim that the flavanoids present in the plants are responsible for the hepatoprotective activity. The present study is performed to reveal that the hepatoprotective and nephroprotoxicity activities of Ixora pavetta in rifampicin induced hepatotoxicity and nephrotoxicity in rat model, to prove its claims in folklore practice against liver and kidney disorders.