Prevalence of insulin resistance among patients with cirrhosis of liver

Abstract

Introduction: Liver cirrhosis is an unique clinical entity in which long-term diabetes mellitus (DM) can predispose individuals to cirrhosis and, on the other hand, long-term cirrhosis of the liver can predispose cirrhosis to DM, secondary to glucose and insulin metabolism. Aims: The aim of this study is to determine the prevalence of insulin resistance in liver cirrhosis.Materials and Methods: This cross sectional case control study conducted in department of medicine in 80 patients for duration of 1 year. All cirrhotic patients irrespective of aetiology were subjected to fasting plasma glucose level and fasting plasma insulin levels and insulin resistance was calculated by HOMA-IR method. Study was statistically analysed.Results: Insulin resistance was found in 62 cases with IR in ratio in 1.64 is 4.6+2.9. with p value is