Histopathology of skin lesions of canine atopic dermatitis in pugs

Abstract

Present study was undertaken to know the histopathological features in canine atopic dermatitis by taking skin biopsy. Skin sample was collected from 30 atopic pugs in 10 percent neutral buffer formalin and tissues were processed by routine paraffin embedding technique and three to five micrometre sections were cut and stained with hematoxylin and eosin. Histopathological findings in CAD were characterised by presence of haemorrhages in the supra epidermal, epidermal and sub epidermal region, congestion of blood vessels, accumulation of serosanguinous fluid in the supra epidermal region and edema of sub epidermal region, spongiosis, mild to severe infiltration of inflammatory cells, perivascular dermatitis, epidermal hyperplasia, hyperkeratosis, cystic dilatation of hair follicles and hyperpigmentation. Suppurative folliculitis and suppurative perifolliculitis was suggestive of secondary bacterial pyoderma.