HbA1c and its association with anthropometric parameters and renal profile in type 2 diabetes mellitus patients in Jharkhand

Abstract

In terms of the worldwide burden, the WHO Global Burden of Disease estimated that around 177 million people in the world had diabetes in the year 2000 and estimates 194 million in the year 2003, and around two-thirds of these people live in developing countries. The projections for the future provide no comfort at all. If current trends prevail, the above figure may well more than double by the year 2025. The present study was conducted on a sample of 200 diabetic patients including both men and women in the age group of 30 – 70 years to assess the anthropometric measurements and HbA1c levels in the selected subjects. The study was an attempt to evaluate the diagnostic value of glycated haemoglobin (HbA1c) in predicting diabetes. Glycated haemoglobin (HbA1c) is routinely used marker for long term glycemic control. Each of the subjects was initially evaluated for Body Mass Index (BMI) and Waist Circumference (WC), and renal profile like Blood Urea Nitrogen (BUN) and serum creatinine (Cr). A detailed clinical evaluation including history and physical examination was done on each subject. The data obtained was collected and the occurrence and pattern of other complications was studied. It was analyzed that there are various factors that all together affects the glucose levels; no single factor shows the result alone. It was also observed that most of the subjects with HbA1c levels were overweight and obese and has the higher side of the Waist Hip ratio. Diet and exercise to some extent plays a role in the control of sugar level.