Synthesis, characterization and biological activity of schiff base derived from sulphanilamide and its metal complexes with cobalt, nickel and copper

Abstract

Schiff base have been prepared by the condensation of sulphanilamide with salicylaldehyde. The Schiff base was characterized by elemental analysis and spectral method. The metal complexes of Co (II), Ni (II) & Cu (II) have been prepared by the reaction with Schiff base. The analytical, spectral and magneticstudy data support the octahedral structure for all the complexes. The biological activities of Schiff base and their metal complexes have been studied by screening the compounds, against microorganisms such as E.coli and S. aureus.