Study of serum levels of cefquinome in goats by using microbiological assay method

Abstract

For this study, 12 goats of either sex were selected. A group of six goats was administered with cefquinome @ 2 mg/kg by intramuscular route and another group of six goats was administered with cefquinome @ 2 mg/kg by intravenous route. The serum cefquinome concentrations in adult goats were determined up to 24 hrs after drug administration by using microbiological assay method. In the present study the therapeutic concentrations of cefquinome were maintained for more than 8 hours (0.08 ± 0.011mcg/ml) after intravenous administration and intramuscular administration and at the time of 10th hr sampling the cefquinome was not detected in serum after either intramuscular or intravenous administration.