A study of mean platelet volume in patients with diabetic and non-diabetic subjects

Abstract

Large platelets are more thrombogenic and thus put the patient at a higher risk status. Mean platelet volume (MPV) is a determinant of platelet functionality and increased MPV is associated with increased risk for myocardial infarction, stroke and transient ischaemic attacks. The present study to estimate MPV in patients with diabetes mellitus (DM) and non-diabetic controls. Mean Platelet Volume in Diabetics and Non-Diabetics. Mean platelet volume (MPV) test was conducted in 100 diabetic patients and 100 non-diabetic subjects of age between 28-58 years, all subjects were recruited from dept of Physiology Maharajah's Institute of Medical Sciences (MIMS), Nellimarla in Vizianagaram district of Andhra Pradesh. The Mean Platelet Volume is high in Diabetics and the values are statistically significant (p value = < 0.0001). This indicates that elevated MPV could be either the cause for or due to the effect of the vascular complications. Hence, platelets may play a role and MPV can be used as a simple parameter to assess the vascular events in diabetes.