Antifungal and phytochemical properties of Tinospora cordifolia, Azadirachta indica and Ocimum sanctum leaves extract

Abstract

In the present study the aqueous, methanol, ethanol and acetone extract of Tinospora cordifolia, Azadirachta indica and Ocimum sanctum leaves extractwere screened for the presence of phytochemical components and tested for antifungal activity against Candida albicans, Aspergillus niger, Aspergillus fumigatus, Microsporum gypseum and Trichophyton rubrum Results revealed the presence of anthraquinones, alkaloids, saponins, tannins, glycosides and phenolics. The acetone extracts had wide range of antibacterial activity against bacterial pathogens than the ethanol and methanol extract, where as aqueous extract were slightly higher antibacterial activity as ethanol extract. Antifungal activity of various extract of leaves of Tinospora cordifolia, Azadirachta indica and Ocimum sanctum would lead to the establishment of some compounds that could be used to formulate new and more potent antimicrobial drugs of natural origin.