A non-invasive method of predicting pulmonary hypertension using plain CT chest in correlation with 2d echocardiography

Abstract

The aim of the study is to evaluate and compare the Plain CT based different vascular measurements in patient with probable pulmonary hypertension and in normal subjects. Images acquired using routine NCCT protocol on 16 slice Toshiba Alexion CT machine and. Reconstructed images were studied in full magnification on standardized media stinal window settings of (W:400/L:20). The widest diameters perpendicular to the axis of main pulmonary artery, right pulmonary artery, left pulmonary artery, ascending aorta and descending aorta are measured using calipers. These respective measurements of 50 normal subjects were compared to the 20 probable pulmonary hypertensive group diagnosed using standard2D Echocardiography criteria.The measurements of MPA,RPA,LPA,MPA/AAo and MPA/DAo in normal subjects are 2.33(SD-0.31),1.84(SD-026),1.74(SD-0.25),0.82(SD-0.10) and 1.06(SD-0.22).The respective measurements in probable pulmonary hypertension group are 3.58(SD-0.30),2.57(SD-0.41),2.71(SD-0.49),1.11(SD-0.16) and 1.47(SD-0.30), which are comparatively higher and statistically significant (P value