Serum Adiponectin in women with polycystic ovary syndrome of different body mass index

Abstract

Background: Polycystic ovary syndrome is an extremely common disorder in women of the reproductive age that is associated with a disturbance of reproductive, endocrine, and metabolic functions. The pathophysiology of PCOS appears to be multifactorial and polygenic. Adiponectin seems to play an important role in the pathogenesis of PCOS, especially in obese women. Objectives: To (1) measure serum adiponectin levels in women with PCOS of different body mass index; and (2) assess possible relation between adiponectin level and the hormonal changes of the disease. Setting: Baghdad Teaching Hospital. Duration of study one year from 2018 to 2019.Methods: 80 women were included in this study, 40 women were suffering from PCOS (study group), and the remainder 40 were healthy women served as a control group. BMI is calculated, then each group subdivided into 2 groups: overweight with BMI≥25Kg/m2 and the normal weight with BMI