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Fourier transform infra-red spectroscopic study in homoeopathic potentized medicines

International Journal of Homoeopathic Sciences · 2020 · Vol. 4(2) · pp. 226–234

Abstract

During Drug-dynamization the produced mechanical energy (~ 404.3 Nm/10 strokes) is presumably transformed to the H-bonded network system of ethanol (medium) that shows the signature in IR/Raman spectral analysis. In the present work, Fourier Transform Infra-Red (FTIR) Spectroscopic studies on different homoeopathic medicines of different kingdom with various potencies have been performed and the results have been compared with that of 91% (v/v) ethanol (the medium). The broad spectrum for all cases (including ethanol) can be decomposed into three Gaussian components centered around 3275cm-1, 3395cm-1, and 3502cm-1. In pure ethanol these frequencies are the signature of the –OH groups of ethanol with strong, weak and dissociated H-bonding. Spectra for different sample medicines have the three bands but the relative percentage of population of different H-bonding for each medicine is dependent on the nature of the drug and its potency indicating that each medicine possesses an individual character in energy patterns in terms of H-bonding pattern and not in the molecular and nano particle nature.

Drug Solubulity and Delivery SystemsAnalytical Methods in PharmaceuticalsPhytochemistry and biological activity of medicinal plantsFourier transform infrared spectroscopyRaman spectroscopyFourier transformEthanolPopulationAnalytical Chemistry (journal)InfraredChemistryInfrared spectroscopyMaterials science

Funding

  • National Chemical Laboratory
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