Nanocomposite modified electrode for cholesterol estimation: A review

Abstract

Cholesterol is a waxy steroid of fat and it plays an important role in the initiation and progression of cardiovascular diseases, so its estimation in blood serum is very important. In this work we report, non-enzymatic electrochemical sensors for the determination of cholesterol with different nanocomposite coated working electrode The surface morphology and the property of nanocomposite were characterize by scanning electron microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), X- Ray Diffraction spectra (XRD) simultaneous TG-DTA-DTG. The electrochemical behavior of cholesterol was studied using cyclic voltammetry (CV) and Square wave voltammetry (SWV). This review is focusing on the synthesis of different type of coating materials for the working electrode surface modification. Present report also compiles the development of electrochemical sensor for trace level highly sensitive quantification of cholesterol.