Study on effect of pantoprazole and ranitidine in canine gastritis

Abstract

The study was conducted for comparative assessment of Clinical-haemato-biochemical parameters and comparative therapeutic evaluation of the efficacy of PPI (Pantoprazole), and H2- blocker (Ranitidine) in clinical cases of Canine Gastritis. Six healthy and twelve gastritis affected dogs were selected for the study based on clinical observations, Hemato-biochemical parameters. The significant Hemato-biochemical alterations included increased hematocrit, PCV, TLC, Neutrophil, Monocytes, and Eosinophils, an increase in serum Histamine and decreased Gastrin levels in gastritis affected dogs. On comparative evaluation, Pantoprazole treated group showed significant (P