Molybdenum: Role in biological system

Abstract

Molybdenum functions as a cofactor for a limited number of enzymes in humans. The primary criterion used to set an Estimated Average Requirement (EAR), which is molybdenum balance in controlled studies with specific amounts of molybdenum consumed. Adjustments are made for the bioavailability of molybdenum. The Recommended Dietary Allowance (RDA) for adult men and women is 45 μg/day. The average dietary intake of molybdenum by adult men and women is 109 and 76 μg/day, respectively. The Tolerable Upper Intake Level (UL) is 2 mg/day, a level based on impaired reproduction and growth in animals.