Therapeutic efficacy of polyherbal anti-diarrhoeal preparation in diarrhoeic goats

Abstract

Diarrhoea has been recognized as one of the most important health problem and leading cause of mortality and morbidity in goats. The Aegle marmelos, Dalbergia sissoo and Holarrhena antidysenterica possesses antidiarrheal activity, which acts by reducing the gastrointestinal motility and gastric secretion and possess lesser side effects than the conventional drugs. The present research work was undertaken to study the therapeutic efficacy of Polyherbal antidiarrhoeal tablet containing hydro-ethanolic extracts of unripe fruits of Aegle marmelos, bark of Dalbergia sissoo and seeds of Holarrhena antidysenterica in diarrhoeic goats and to study the haematological profile in diarrhoeic goats. Total 25 diarrhoiec goats were selected and treated with polyherbal antidiarrhoeal tablet (600 mg) @ 1 tablet orally twice a day for 5 day along with fluid and supportive treatment depending on severity of case. The efficacy of Polyherbal antidiarrhoeal tablet was judged on the basis of restoration of faecal consistency to normal and improvement in haematological parameters in diarrhoeic goats after treatment. The mean rank of faecal consistency score was normal in diarrhoeic goats after treatment with Polyherbal antidiarrhoeal tablet. The haematological profile study showed significant (P<0.01) improvement in altered PCV (%), TLC, TEC, neutrophils (%), lymphocytes (%) and eosinophils (%) on 5th day post treatment as compare to their corresponding values on ‘0’ day (before treatment). The study concluded that the polyherbal antidiarrhoeal tablet containing Aegle marmelos, Dalbergia sissoo and Holarrhena antidysenterica found effective and safe remedy in inducing recovery in diarrhoeic goats with improvement in haematological parameters.