Moxifloxacin and its therapeutic uses in animals: An overview

Abstract

Fluoroquinolones are a group of antibiotics that have increased in numbers in recent years. Their usefulness has greatly expanded with the introduction of several new quinolones having improved properties compared to older members. Moxifloxacin is a new fluoroquinolone antibiotic used to treat a number of bacterial infections in animals. It includes urinary tract infections, pneumonia, conjunctivitis, endocarditis, tuberculosis, respiratory tract infections, cellulitis, anthrax, intra-abdominal infections, endocarditis, meningitis and sinusitis. As compare to older fluoroquinolones like enrofloxacin, ciprofloxacin and levofloxacin, moxifloxacin is found highly effective, bioavailable and with less adverse effects. It is well absorbed after different routes of administration like intravenous, intramuscular and oral with an absolute bioavailability of 95% and the plasma half life is between 8.15-11.70. This review article will explain about the different uses of moxifloxacin in different disease conditions.