Evaluation of the antimicrobial activities of root bark and leaves extracts of Ziziphus spina Christi grown in Sudan

Abstract

The antimicrobial activity of Zizyphus Spina Christi roots bark and leaves different extracts (petroleum ether, chloroform, ethanol and water) and sub fraction extracts of ethanol extract (petroleum ether, chloroform, ethyl acetate and n-butanol), were examined for their antimicrobial activity using cup-plate-agar diffusion method against four bacteria species, (staphylococcus aura, (S.a) Bacillus subtilis (B.s), Pseudomonas aerugionosa (Ps.a) and Esherichia coli (E.coli)), and two fungal species; (Candida albican (Ca.a) and Asparagellus Nigar (Asp.n)). Most extracts had considerable activity against tested organisms. The results obtained from the diameters of the growth inhibition zones of microorganisms (bacteria and fungi tested) provided good evidences that the ethanol crude extract of the root barks of zizyphus spina Christi, could be consider as promising source of antimicrobial ingredients.