Pre-clinical screening model organism to study Parkinson disease: Caenorhabditis elegans and its utility

Abstract

The people suffering from mental disorder are frequently high at 21st century due to lifestyle. Alzheimer type or Parkinson’s disease is an old age disorders observed in many people in almost all countries and impose on challenge to research field for drug discovery for preventing and restoring the mental health of people. Many model such as Zebrafish, flies, anurans and nematodes (C. elegans) were used to study Parkinson disease but C. elegans are the best model for Parkinson’s disease because of its special character like short lifespan, transparent and micro in size help the researcher to discover drug very easy, fast and in an economically feasible manner.