Risk assessment due to dietary exposure of quinolones and Penicillins antimicrobials residues in milk

Abstract

This study was conducted to determine exposure risk to quinolones and penicillins residues in milk consumed in the Hisar and aimed to estimate dietary exposure. The risk assessment due to dietary exposure was done on the basis of per capita availability of milk in Haryana and India by calculating hazard quotient for each analyte. On the basis of calculated dietary intake and acceptable daily intake available, the hazard quotient was calculated and it was found 0.032, 2.58 and 0.0004 for enrofloxacin, amoxicillin and cloxacillin respectively for population of India whereas for Haryana population, hazard quotient was 0.0145, 1.28 and 0.0002 for enrofloxacin, amoxicillin and cloxacillin respectively. The estimated dietary exposure based on the data on average consumption of milk suggested that people in India as well as Haryana are not at risk for dietary exposure of ciprofloxacin, enrofloxacin and cloxacillin residues. However, with respect to amoxicillin, the risk of dietary exposure is slightly more as compared to ADI value.