Efficacy of buparvaquone in bovine theileriosis in Haryana

Abstract

Theileriosis is caused by protozoan parasites of the genus Theileria which infects lymphocytes and erythrocytes of ruminants. The diagnosis of theileriosis is usually based on clinical signs and the demonstration of piroplasms and schizonts in blood and lymph node biopsy smears respectively. A 23 days old female Holstein calf was presented to Teaching Veterinary Clinical Complex, IIVER, Rohtak, Haryana with a history of high fever (104.7 ˚F), anorexia, dullness, staggering gait, absence of suckling reflex, slight pale mucus membrane and presence of enlarged pre-scapular lymph nodes. Complete blood count (CBC) revealed low red blood cell counts (TEC), haemoglobin (Hb), packed cell volume (PCV) and mean corpuscular haemoglobin concentration (MCHC) values indicating moderate degree of anaemia caused by Theileria spp. The peripheral blood and lymph node biopsy smears exhibited the presence of piroplasms and Kochʼs blue bodies respectively. The animal was treated successfully with a single dose of buparvaquone @ 2.5 mg/kg BW by deep intramuscular route along with supportive therapy.