Haematological and biochemical parameters altered in tuberculin reactor cattle

Abstract

Tuberculosis is a chronic granulomatous infectious zoonotic disease prevalent in developing countries resulting high mortality and economic loss. The present study was taken up to understand the correlation between different haematological features in the typical cases of tuberculosis in dairy herds with that of comparative tuberculin positive, inconclusive and negative reactors. The study was carried out in unorganized dairy farms of peri-urban dairy farms of Guwahati city in Assam. A total of 44 milch animals were selected showing symptoms like TB in the age group of 1-8 years for the study. Single Intradermal Comparative Tuberculin Test (SICTT) was performed using bovine PPD and avian PPD. Blood samples were collected from all the tuberculin injected cows for haematological and biochemical analysis. A number of 11 positive reactors, 14 inconclusive reactors and 22 negative reactors were selected for studying the haematological and biochemical changes. In positive reactors there was significant increase in WBC, lymphocyte, THR, MPV, SGOT, SGPT and significant decrease in RBC, Hb, neutrophil, eosinophil, basophil, PCV, cholesterol, Ca2+ and phosphate compared to negative reactors (P