The impact factor of the thiirane group in organic compounds on their predicted pharmacological activities: A brief review

Abstract

The present review describes the biological activities of organic compounds containing the thiirane group. We looked at how the thiirane group can influence the biological activity of aliphatic, cyclic and aromatic hydrocarbons, as well as the organometaloid compounds containing thiirane group. The structures and predicted activities of these compounds are available. With the computer programme PASS and based on structure–activity relationships (SAR), some additional activities are also predicted, which point towards new possible applications of these lipids. This review emphasizes the role of thiirane containing compounds as an important source and potential leads for drug discovery and they are of great interest to chemists, physicians, biologists, pharmacologists and the pharmaceutical industry.