Evaluation of antiproliferative properties of Lavatera cachemeriana roots

Abstract

Brest cancer is the leading cause of deaths across the world and plant derived bioactive molecules are considered as potent and safer agents to tackle and prevent therapeutically challenged breast cancer incidences. The current study investigated In vitro anti-proliferative activity of Lavatera cachemiriana methanol root extracts against breast cancer cell line (MCF-7) through MTT assay, L-6 cell line acted as a negative control. Results have demonstrated that extracts showed insignificant levels of anti-proliferative activities against tested cell lines (IC50> 1000 µg/ml). The morphology of both treated and untreated cells was same with no changes reported. In conclusion, the methanol root extract possesses no marked anti-proliferative activities against breast cancer cell line at the tested extract concentrations.