In-vitro anti-inflammatory activity of ethanol extract of Crotalaria longipes

Abstract

Ethanol extract of Crotalaric longipes aerial part (Fabaceae) was judged for anti-inflammatory activity by In-vitro. Qualitative phytochemical analysis revealed the presence of alkaloid, flavonoid, phenol, glycosides, saponins, steroids etc. In-vitro anti-inflammatory activity was calculated using, proteinase inhibitory activity, albumin denaturation assay, membrane stabilization and antilipoxygenase activity at different concentrations. Aspirin was employed as standard drug. The results showed that Crotalaric longipes ethanol extract at a concentration range of 100 -500 µg/ml significantly (p<0.01) protects the heat induced haemolysis. The results obtained the present study indicate the ethanol extract of Crotalaric longipes can be a potential source of anti-inflammatory agents.