Shuddha Sveta Gunja - purified (Abrus precatorius Linn.) white variety experimental Pharmacology as anti-diuretic activity

Abstract

Purpose: In present study was undertaken to investigate the Anti-diuretic activity of Hydroalcoholic seed extract of Shuddha sveta Gunja (Abrus precatorius Linn.) in Albino rats. Method: The method of Lipschitz et al. was employed for the assessment of Anti-diuretic activity. Four groups of six rats were taken for the study. Groups: Normal, Control, Standard, Test-1 (200mg/kg), Test-2 (400mg/kg).Results: The study showed that high and low doses of HASEAP (Hydro-alcoholic seed extract of Abrus precatorius Linn.) along with the effect on electrolytes like Na+, K+ and Cl- showed significant Anti-diuretic activity.Conclusion: It may concluded that Hydroalcoholic seed extract of Shuddha sveta Gunja (Abrus precatorius Linn.) possess Anti-diuretic activity in a Dose dependent manner which appeared to be comparable with that of the Standard drug Frusemide.