Chemical constituents of Haliclona: An overview

Abstract

Marine sponges (Porifera) are rich sources of bioactive compounds. Marine sponge of the family Haliclonidae have proved to be a rich source of nitrogen containing metabolites with various bilogical activities. E.g. halitoxin, xestospongins, sarains, papuamines and haliclonadiamine. Sponges of the genus Haliclona are well known for producing a variety of secondary metabolites, most commonly bioactive alkaloids. The genus Haliclona has a history of providing diverse structures. The present review article compiles the different classes of compounds isolated from the genus Haliclona and their bioactivities. A wide range of bioactivities like antimicrobial, hemolytic, hemagglutination, antibacterial, antioxidant, anti-inflammatory and anticancer activities have reported from Haliclona