Comparative evaluation of In vitro antioxidant analysis of various leaves extracts for selected medicinal plants

Abstract

Aegle marmelos, Cocculus hirustus, Grewia asiatica and Populus deltoides sp. leaves extracts were evaluated for their antioxidant potential with various in vitro tests including nitric oxide radical scavenging assay, reducing power assay and total antioxidant property by phosphomolybdate method. It was found that nitric oxide radical scavenging property was highest for A. marmelos leaves acetone extract (AMLAE) (57.65 ±0.46 µg/mL) while the highest reducing power ability was exhibited by A. marmelos leaves aqueous hot extract (AMLAqHotE) (871.09 ±14.52 µg/mL) and P. deltoides leaves acetone extract (PLAE) (61.78 ±1.74 µg/mL) demonstrated highest total antioxidant property as estimated by phosphomolybdate method. This conclude that the leaves extracts of these plants have strong potential for scavenging free radicals thus can be used for synthesis of potent antioxidant drug component for various diseases caused due to oxidative stress like cancer, aging, inflammation, cardiovascular diseases, neurodegenerative diseases, and liver injury etc.