Efficacy of anthelmintics against GI Helminths of Cattle in Pulwama district of South Kashmir

Abstract

The present study was undertaken to evaluate the therapeutic efficacy of different anthelmintics viz, ivermectin, fenbendazole, closantel and oxyclozanide under field conditions against gastrointestinal (GI) helminths of cattle in Pulwama district of south Kashmir. A total of 90 cattle (EPG ≥ 100) infected with GI helminths were selected and divided into six groups of 15 animals each. The animals in group 1 were treated with fenbendazole, group 2 with closantel, group 3 with ivermectin and animals of group 4 were kept as infected untreated control for nematode infections. The animals of group 5 were treated with oxyclozanide and the animals of group 6 were kept as infected untreated control for trematode infections. For determining the efficacy of fenbendozle, closantel & ivermectin, the faecal samples collected on '0' day before treatment and on 7th & 14th day post treatment were examined quantitatively by Modified Mc Master’s technique. For determining the efficacy of oxyclozanide drug in addition to 7th and 14th day post treatment collection, one more collection was done on 28th day. On the basis of Faecal Egg Count Reduction Test (FECRT), ivermectin, closantel and fenbendazole were found to be 100 per cent effective against strongyle worms on 7th and 14th day post treatment. Similarly oxyclozanide was found to be 100 per cent effective against paramphistomes on 7th, 14th and 28th day post treatment.