In-vitro anti-arthritic and anti-platelet activity of Galinsoga parviflora Linn.

Abstract

The present study is objected to evaluate the methanolic leaf extract of Galinsoga parviflora for acclaimed anti-arthritic activity using in-vitro inhibition of protein denaturation model as well as as anti-platelet activity. Acetyl salicylic acid (Aspirin) was used as a standard drug. Phytochemical analysis of methanolic extract of Galinsoga parviflora has indicated the presence of steroids, flavonoids and terpenoids types of compounds. Since these compounds are of pharmacological interest, coupled with the use of this plant in traditional medicine, i.e. for possible anti-arthritic as well as anti-platelet activity. Results revealed that the methanolic extract of Galinsoga parviflora at three different concentrations (100,250 and 500 mcg/ml) possessed significant anti-arthritic well as anti-platelet activity as compared to standard used drug acetyl salicylic acid. The plant extract showed dose dependent activity.