Antibacterial activity of green synthesized copper sulphate doped gold nano particles from the leaf extract of Aegle marmelos L.

Abstract

Biosynthesis of nanoparticles is a valuable method and highly safe with low cost. Gold nanoparticles have an enormous medical application, in recent years. This study demonstrates an optimized biosynthesis for stable gold nanoparticles (AuNPs) from methanolic extract of Aegle marmelos leaves. The biosynthesized gold nanoparticles characterization using UV-Vis spectrophotometer, Zeta seizer, X-ray diffraction, TEM, and FTIR. UV-Vis spectra of gold nanoparticles showed maximum absorption peak at 549.10 nm. From the TEM images, the size of AuNPs was found to be about 38.2±10.5 nm. The synergistic effect of biosynthesized AuNPs gave highest fold increase against E. faecalis, K.pneumoniae and K.oxytoca as standard antibiotics respectively.