Comparison of serum mineral levels in perimenopausal women with surgical menopausal women: Analytical cross sectional study

Abstract

Aim: comparison of serum mineral levels in perimenopausal women with surgical menopausal women. Methods: The present analytical cross sectional study was conducted on patients (out patients and in patients) in Department of Obstetrics and Gynecology, Kamla Nehru Hospital, attached to IGMC Shimla. Group 1 (N=60): Perimenopausal women aged 40-45years as control. Group 2 (N=60): Women who had undergone hysterectomy with bilateral salphingoophorectomy at least 6 month ago. Serum calcium was estimated by Arsenazo colorimetric method in mg/dl after the relevant quality control checks. Serum magnesium was estimated by magnesium by Xylidyl blue colorimetric assay in mg/dl after the relevant quality control checks. Serum phosphorus was estimated by Molybdate U.V. method in mg/dl after the relevant quality control checks. Results: In the present study the mean age of post-surgical menopausal group was 46.0 years and in the perimenopausal group the mean age was 42.4 years. Mean parity in post-surgical menopausal group was 3.03 and 2.5 in the perimenopausal group. Conclusions: The prevalence of osteoporosis is very high in this part of India. Both peri and post-surgical menopausal women have lower levels of serum calcium, magnesium and phosphorus.