Prealbumin variation in neonatal bacterial infections

Abstract

This is a prospective cross-sectional study carried out at the department of pediatric of the Diamniadio children's hospital in 2016. This includes subjects aged between 0 and 28 days admitted for neonatal infection according to clinical and anamnestic criteria. Prealbumin assay was carried out using the immuno-turbidimetry technique with the A15 automate of Biosystems®. In 50 newborns, bacterial neonatal infection was confirmed in 24% of the population. Prealbumin concentration of newborns with isolated germs (179.08±108.87 mg / L) is lower compared to the group where no germ was isolated (199.41±108.87 mg / L) but without significant difference. However, Gram-negative infection was responsible for a greater decrease in prealbumin. It is therefore important to include the dosage of prealbumin in the monitoring of neonatal bacterial infections to prevent complications.