Tunicamycin – A born fighter against CORONA

Abstract

One of the perilous threat to humans are Viruses. A greater risk of mortality and morbidity in mankind are caused by most of the viruses. Unfortunately, corona virus stood as a monster in the present scenario. The external envelope of the viruses are comprised of proteins namely glycoproteins. The primary target in viral replication is to interrupt the n-glycosidic linkage thereby obstruct the signals from endoplasmic reticulum to the envelope. This particular area has gained more scope in scientific research. The drug namely tunicamycin has grabbed scientist’s attention in prohibition of viral propagation by showing its effect on endoplasmic reticulum resulting in stoppage of the signals, envelope breaking and inhibiting the interactions with cellular membrane.